ALS, also known as Amyotrophic Lateral Sclerosis, also known as Lou Gehrig's disease, is a neuro-degenerative disease that affects nerve cells in the brain and spinal cord, leaving them unable to send impulses to the muscles. The disease can leave victims entirely paralyzed or dead.
As I mentioned in the video, this thing is working. The charity has reported donations more than 8 times their normal amount since this has started, and awareness is at an all time high. Technically the rules say you have to donate if you don't get drenched, but I'll be donating a little. If you can afford it, you should too.
Where you can donate: link
More info: link